i won't touch focal until someone make sure they improve the reliability of their drivers.. with the elear and utopia dying left and right.For open headphones I have just got the Focal Clear and it sounds great on the ZX300 even on SE which really surprises me. Also I've tried the HD660S and is nice out of the ZX300 though similar to the older HD650 it's a warmish phone so I'm not sure they fit your quest for good female vocal. For closed cans the Z1R can be driven well from the ZX300 as well but it's not a female vocal focus phone out of the box, but if you dial in a bit of EQ to tone down the bass and boost the mids a little you can make it work well with vocals.
yeah, the hd 660s and the z1r is on my list. i mostly listen to rap and female vocals. which one do you think is better for both?