I also got the sick and nauseous feeling for nearly a month when I got my SE846, but after getting accustomed to them through brief, controlled listening sessions I feel fine now listening to it. You just need to listen to it more and get used to the sound ("brain burn in"). I was upgrading from a Westone 4R and the sound was much more lively, visceral and mid-forward, all these contributed to an overwhelming fullness of sound flowing into my ears and I guess I got dizzy and nauseous from that initially, until I stuck with it and after a month of use it got way better. I now have the same nauseous, overwhelmed feeling listening to my new Laylas because with the comply tips they sound too 3D, warm and full.
I tried my SE846 out of a Mojo connected to an AK120ii and did not find it more pleasant than simply playing it out of the DAP alone. I talked with my shop and think that due to the 846 having such a low impedance and not needing much power to drive, the Mojo simply made it way too brutal and powerful. Everything felt like it has too much energy, sounds were harsh, grazing, and overly bright. Sibilance was very apparent and more noticeable than straight out of the 120ii. I was on the blue filter and have not tried black filters with the Mojo.
My very brief impressions with the Layla out of Mojo was positive however, the bass tightened and moved faster, and improved the clarity and air. I think the Mojo has quite a clean, clear, hi-fi sound, and therefore pairs better with more warm, lush iems than bright ones.