It's not a huge change from my last version, but I got a 1TB desktop external for the office, Previously, I was carrying a mini external 1TB to and from work every day, keeping it synced to my home machine with GoodSync. Now I have a copy of my entire collection at work, and I'm using GoodSync2Go on the drives themselves. This way, I don't have to carry anything to work at all, unless I want to bring the mini drive to act as a sync-ferry between home and work drives. It also means I now have an offsite backup, finally, for my most precious material possession of all, the data on those drives. One copy at home, one copy at the office, one portable copy. I've also got it set up so that the ferry drive mounts as Z: on both computers, and the main drive for each mounts as E: - this way, the iTunes library in its entirety can always point at E: and work the same on both computers, since they're identical to the drive letter. Anything I change on one end is reflected on the other, once synced, with zero hiccups.
Triple backups + offsite backup + effortless sync... for the first time in my life I actually feel completely safe about the music collection.
Also, this is just a plain better shot of my setup over-all.
iTunes -> Bifrost Uber USB -> Pyst -> Valhalla -> T70