I haven't heard M1S but going purely off of the specs, I'd say almost certainly no, not enough power. My xDuoo X3 gives 250mW into low impedance load vs. only 180 mW from M1S specs. To use my player without an external amp I have to set volume to nearly 100% and the dynamics are sorely lacking. M1S would probably not even get loud enough. Edit: Oops you said X1S. That thing can put over a watt into a low impedance load! Possibly a good match but I can't speak from experience.