Lots of great setups on here... Time for me to add mine to the collection....nothing fancy, but its my main rig and I like it....
Early 2008 iMac (2.4GHz, 4GB DDR2, WD Black 1TB hard drive, ATI Radeon HD2800 XT video)
WD Blue 500GB 2.5" drive in notebook housing (under screen)
4x 1TB HDD (Seagate & WD) hdd on Airport Extreme USB connection (not in picture, under desk)
Optical TOSlink to Zero DAC/Amp (left, bottom)
RCA to Darkvoice THA332 (left, top)
Magicwand tying Bluetooth Mac keyboard and Magic Trackpad together (love that!)
Macessity Lowkey Stand w/ USB 2.0 hub in front
Mix of FLAC, ALAC, 320MP3 run either through iTunes w/ BitPerfect or Decibel (depending in format)
Cans in pic - DT770 Pro 80, Senn HD650