I don't have fit issue with both Roxanne 2 or Layla 2 universal. They are both as comfortable as my JH16pro CIEM.
The initial few days with my Roxanne 2 was finding the wrong tips to use, with the standard tips provided all not providing optimal balance of comfort vs seal, thus the discomfort issue initially.
Purchased the S size comply tip (tried the Medium that fits nicely with my XBA-Z5 and ASG2.5, becomes too large on the Roxanne/Layla 2) and it provides the perfect seal and comfort. Can wear it on my whole 8-hrs flight last month without any discomfort.
Realised that the bore is thicker on the Roxanne/Layla 2, and most tips that I used to have are no longer useable for my ears as they become too big. Tried Sony hybrid, silicon tips, and Spinfits of 2 different packaging, using S, M, and L size. All can't get the same seal and comfort that I get from Comply Small tips.
Problem is you can only find Medium size Comply tips in most stores, and you will need to order from overseas for the S size.