I2S should be best, in theory and I suppose if implemented properly with transformers (like the Singxir Su-1), but I have never used I2S. USB is crap for audio in general, so I heard. It also does not do native DSD but DoP though apparently that does not affect sound. I am surprised why even expensive DAC do not have I2S. It seems like there is a conspiracy to avoid the best sound by not allowing I2S input so it never sounds at its best and so one will need to buy more USB conditioners etc. Forget the USB may be best approach. If I don't want DSD, this may be best solution:USB Vs I2S, we could debate a long time...
I did different tests in the past (USB Amanéro) Vs I2S... I2S has always been a winner (It's the native language of DACs, no conversion done end-to-end).
But I never tested SOtM so maybe it's different...
The best I2S combo I know (with computer) costs 1700 €:
Pink Faun I2S bridge + Clock OCXO upgrade + External linear Power supply + Pink Faun IL-2 I2S (HDMI - HDMI) interlink
The best USB combo I know costs 2400 €:
SOtM SMS-200 Ultra + SOtM SPS-500 + Good USB cable (300€) + Singxer F1 USB (Replace Amanero on R2R 7)
Which one is the best ? I don't know. But with the first (I2S) combo, you achieve very high performances.
Schiit: http://www.schiit.com/products/eitr
Ideally a music streamer/player with dedicated I2S feeding into DAC directly is best, and most simple. I have not found an affordable one. Mano ultra seems promising but can only do stereo and limits the DSD to 64 I think (why??!!). For me the whole painful effort of playing downloaded music (instead of CD/SACD) is to get super Hi-RES! Really, I would not bother to get DSD64 for computer audio which is same as SACD, So DSD256 or DXD etc.
For the SU-1, there has been comments that the AC power can dirty the pathway again so some people recommend converting it to pure DC using LPS but that seems really complicated and needs some DIY mod.
Or one can try the modified SU-1 that cleans up the AC pwr:
https://kitsunehifi.com/product/kte...6-dop-free-shipping-with-coupon-code-singxer/
https://www.magnahifi.com/en/websho...ion-su-1-digital-xmos-usb-audio-bridge-dsd512
I don't know which one would be better. But perhaps one can do without the Regen before it and still sound good enough.