I think you would learn a lot if you tried building your own amplifier starting from simple designs. Nothing beats hands on experience. Even building some very simple amplifiers and seeing how changes in design and parts affect the sound of the amplifier - in sounding like anything or nothing. Nothing will preclude you from doing any blind testing either.
Here is a great resource for you to get started and it shouldn't cost you that much money:
http://tangentsoft.net/audio/
You will realize that even seemingly innocuous things such as putting capacitors in the signal path (to block DC) or using opamps with different specs affects the sound. You will realize the the design O2 is really not that special. The location of the volume pot is interesting, but that's about it, and even then, it's got some downsides, and it's already been done before. A well designed semi-portable CMOY with a good power supply circuit could actually be a better amp (more transparent) than the O2 for easier to drive headphones.
Until then, in the absence of any meaningful data, test results, or personal experience, you just have a hypothesis no better than any of the more seemingly outlandish subjective claims. Sorry, but that's just how the scientific method works. Observe, measure, postulate, attempt to predict / correlate, observe, measure, measure more, measure more, gain confidence -or- throw out BS, adjust, measure, observe, measure more, etc.