I personally prefer the Hifiman tuning, but this is a bit subjective. The Audeze house sound all has a similar target. It's a darker sound with a great seal and good bass extension (sometimes need a bit of EQ but will have much better impact than the Ananda). The 2C in particular is known for a bit more problems in the treble area, but if you are treble sensitive or listen to genres where this might be an issue (EDM, Metal), then you might appreciate this. Many people do extensive EQ'ing on these to balance them out a bit.
The only one I've tried was the LCD-GX personally. While the build quality was very rugged, I still consider them to be a somewhat fragile headphone. The seal is so good on these, you definitely have to be careful to not put too much pressure on the diaphragm. I've already mentioned the weight, which you said to ignore.