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Yeah I'm really cautious about buying DACs/amps/cables as there is a ton of marketing jargon that gets thrown around by the manufacturers. After reading some of the articles written by the designer of the Objective 2, I'm opting for more real-world testing before purchasing a product. Even with the E11 amp, the specs listed on the box aren't real-world tests.
As for the synergy stuff, I'm not a fan of it but evidently many people seek it. The O2 happens to have very good synergy with the M-100's for the most part.
I am cautious, including of that guy's claims. He probably means well, but he was banned for a reason.
The O2 is a great amp, but probably overkill.
The E12 is cheaper and also a great amp... but probably also overkill.
Something like an E11 or cmoy is probably more cost-effective and thus "better suited" for the M-100.
That's what I meant by synergy & cost effective... The E12 is neutral and probably will pair well with almost any headphone, but it's higher powered and higher cost than "good enough." My idea of the use-case-scenarios is a good budget, high quality amp that will scale between portable headphone use (amp is sized like a large smartphone) and with high-impedance headphones at home that need more volume. Similar to how people have reviewed the E9 as an effective (cost & performance-wise) amp to use with hard-to-drive headphones, the E12 is somewhere between that and the portable, low-output-impedance E11.
Based on my experience, research, & taste, if the M-100 was my only headphone, I'd probably stick with an E11 - I like the sub-bass boost option and the rechargeable/replaceable battery. If I only used high-impedance or low-sensitivity headphones, I'd consider the O2 or better yet a wall powered desktop option. The O2 and E12 both fight for kinda the same space, if I had a bunch of headphones (short of a Stax) and wanted to transport my rig sometimes, but I like that the E12 is slimmer and can easily slip into my pocket (by itself, it's about the thickness of my wallet and the height of an iPhone5). I don't have a 250 ohm plus headphone
yet, but I may in the near future. That's my input, not everyone will agree with me, but hopefully there is enough info for someone else to choose what they like.
I'd just like to add, I've avoided external-DAC jitter problems and stuff by sticking with my iPod as a music player with line-out, and my main cable criteria is that it's not corroded and, if it's passing analogue, that it is made of copper. I'm a big supporter of not chasing marketing magic.