I use poweramp myself when listening on my Sony z1c
My settings are shown in the pic below.
Basically the numbers along the bottom are the frequency that will be affected by moving the slider up or down in order to boost or cut respectively, that part of the frequency spectrum.
So going from my example I have cut around 125hz to 250hz to reduce any mid bass bloat, and then around 8k to reduce the lower treble as I'm very sensitive to that part of treble. I'm no expert but I think that's the area that people refer to as being sibilant when it is too prominent.
Of course the eq will vary for you as everyone has different ears, equipment and files to play from.
As a reference I listen to mostly edm from 320kbps mp3s, but as they say ymmv.
Again I'm no expert and I'm open to any suggestions regarding my technique.
Hope this helps!