I'm using headphone out because i don't have proper desktop amp at the moment (i only change opamps in IV position)
First i went from stock to LME49720 and there was noticeable improvement in terms of clarity, details and soundstage. There was a loss in bass quantity but increase in quality.
Then went from 49720 to 49990 (bought them from
frugalphile) and improvement was even bigger. Not only there was even more details, but the sound was smoother (less fatigue).
This time bass also gained some quantity back. Imaging and sound separation in particular were exceptional.
Then went from LME49990 to AD797BR (bought them from audjade_chn) two weeks ago.
My Q701 went completely berserk. One would call this an out-of-head experience. I don't know what to say really, its that kind of sound that shuts you up and you just want to listen to music