Yes. (drummer) I started off with the 535's. Used them for over 5 years before switching to the 846's, and used them for a couple of years before finally making the leap into custom IEM's. Both served me well. Yes, I use the a12t's. (custom) Yes. Without a doubt, the u12t's are better in every possible way.
Again, you are talking about comparing a Ford Pinto to a Rolls Royce though, in performance and price. You are a musician? have you given any thought to custom in-ear monitors? There are lots of advantages, and I guess disadvantages, depending on what you are used to, sound isolation is one of them. Stage volume will be dramatically cut which is usually good depending on how you have your monitor mix, you may need to setup ambient mics to hear the audience, etc. IIn the case of 64 audio they use a technology called Apex. "There are three levels of isolation provided by apex, -20dB (m20), -15dB (m15), and -10dB (mX). The m15 allows for slightly more ambient sound than the m20, and helps temper the bass. The mX reduces the ambient noise isolation to only -10dB, but in return transforms earphones into a mastering-grade tool with a very resolved sound signature. Each of our in-ear monitors is built with a specific apex module in mind, however, our standard external apex modules are designed to be replaceable, so you can rotate between levels of isolation and sound flavors." Apex is used on universal and custom mold IEM's. I believe other manufacturers have similar ambient technologies for stage volume.
I also love that I don't have to worry about ear tips, tip rolling, etc. I have a perfect fit and seal, every time. I say if you have the money and you want a set of CIEM's the a12t's will serve you and bring you enjoyment for a very long time. 64 Audio also has fantastic customer service. Reach out to them. I think you should demo a few of there models. I'd suggest the A4, A6, u12t, and u18t. If you're a drummer or bass player and like or want the strongest bass possible I'd check out the N8's. I hop this helps you.