The Shure 846 IEM's, seriously? The ones with multiple filter-rings for different sound signatures? Daaaang son, you have WAY more money to spare on audiophile-equipment than I do, I'm pretty jealous right now

Those things are like a thousand bucks, right? Where'd you get them?
Anyway man, about the amp. . .with the Shure 846, I wouldn't use the amp at all, ever, if I were you! There's just no need. Those things, like other IEM's, are very low-impedance because they are meant for portable use more than anything. In fact, the impedance on the 846's is especially low, at only 9 ohms. There is no reason to drive them from an amp, and in fact, you SHOULDN'T drive them from an amp, it could end up, worst-case-scenario, blowing-out drivers in the earphones due to over-driving them with too much power for them to handle! Also, make sure that when driving the 846's from the X3, you have the player set to low-gain, not high-gain.
Headphone amps are meant for HIGH impedance headphones,j and won't benefit the sound at all in something like the majority of IEM's.
Also, dang, if you were able to spend a thousand dollars on a pair of earphones, why don't you splurge and get a really super high-end Astell and Kern music player instead of the X3, or at least the X5? If I were you that's what I'd do
One more question. out of curiosity, what filters do you generally use on the 846's, from among the custom filters that come with it for changing the sound?