Sorry I have to break my promise to post any more, but Anonanimal, what you said is not the same thing.
A DIYer could indeed make mistakes installing parts on a PCB, this is not just trimpots, nor is it restricted to the β22. But one could only go so far to prevent something like that from happening.
Now about the gain structure of the O2 amp and its low input overload margin, is a problem that cannot worked around in many circumstances, even if the builder/user has full knowledge of the limitations. For example, I find that with a γ1 or γ2 DAC feeding an amp with a gain of 5x just about perfect for my Sennheiser PX100 headphones (which are portable). If you were to build an O2 with a gain of 5x and use it with these DACs, it will clip badly (on battery power or AC power) regardless of where you turn the volume knob. If I was to use the O2 amp for my Sennheiser HD600 or HD800, I would prefer a bit more gain, which would make matters worse.