IDK how much better is the Red/Cobalt vs the original version, but I'd take ES100 any day and I sold Dragonfly + DAP soon after I got ES100. To my belief and ears, that possibility of ~10% increase of "better sound" (which I can rarely ever able to distinguish) of wired options is just not comparable to ES100's wireless convenience (and the sound is damn good too). Best $100 I've ever spent on audio gear, worth every single cent.
That's all with the shilling, ok so Dragonfly black sound is a tiny bit cleaner and blacker background vs ES100. Again, I can hardly tell unless I sit down and look for them.
BTW, Fiio is releasing BTR5 soon later this year and the specs is pretty great, might be a worthy ES100 replacement (unless Radson does their magic again with something like ES100 v2)