I think HD650 is playing some games with us, at least it did with me during burn-in. Sounds like a $50 headphone was my first impression out of the box, but luckily I had heard a somewhat burned-in one in the shop. Later I thought that the main burn in was made after 75 hours, now I would rather say 100 - 150 hours. During this process it seems to change sound many times.
After 150 hours I got my Zu Mobius and was happy of the sound and that it was close to the neutral balance of the burned-in stock cable but with improved transparency and bass. After some burn in, this cable began to sound way too warm and didn't retain balance until about 100 hours. On one of the tracks that sounded too warm, I later understood that the sound of the violins was intermixed with concert hall ambience, which in a later phase were seperated. It is hard to say if the headphone burned in further after 150 hours becuase I switched cable, but I am inclined to believe it.
I think that one reason for these sometimes subjectively drastic changes during burn-in is the high resolution of the headphone, putting the microscope on anything and small changes in for example tonal balance becoming very noticable. After 250 hours I am very satisfied with this headphone I agree with all of JaZZ's points a few posts before in this thread, that it has a neutral tonal balance, is very clean and resolved without overemphasizing detail, you don't hear DETAIL but all the details when there are any to be exposed.
With the Zu, bass is magnificant with high volume and very tight. On one of the tracks on the newly remastered On the Beach (Neil Young), it sounded during the burn-in phase like I had a subwoofer in the room at the opposite wall. This seems to have been some phase-shift that later disapperad with the drum moving inside the soundstage. The bass is very loud and tight and filling the room on the track On the Beach. Yes, I wrote fill the room because this is the illusion. Here crossfeed is needed to get the bass really tight, without it has a little looser character like space sound. I wondered if this level of bass was overmephasized but think not. The bass is not something that is in the character of the headphone/cable combo and always present. Rather you get what you feed into the headphone, from nothing to very loud depending on the recording. I would rather say that the bass is reproduced to its full volume and extension, which is unusual for headphones (as well as most speaker systems). There is no tendency of compartmentalisation of bass and midrange which are well integrated with a seemless transition. The separation is also very good so a high volume of bass does not interfere with perception of midrange and highs.
It can take some time to be used to this bass quality as well as the low distortion and cleanness in midrange. I regard the midrange and treble to be of very high quality but have not made a full evalutaion yet. One reason is that the Mobius is stated to need 250 hours for full burn-in and improvements in transparency and smoothness can be expected. The other reason is that I feel a need to visit some live concerts with acoustical instruments to calibrate my own references.