No. There can be discrepancies in amplitude and frequency, but if there's a resonance in the coupler, the same thing will happen in your ear canal.
Resonance is just energy trapped or accumulated at a particular wavelength. The length (and volume, if you have transverse modes) plays a role, but the whole point of the coupler is to mimic the length and volume of the average ear canal. Likewise, the materials used (
@crinacle's vinyl coupler) will mimic the inside of the ear canal - which also isn't perfectly reflecting. Measurement differences aren't an error. The fact that you'll hear something slightly differently to me, doesn't mean your ears have an error - it just means they're slightly different.
There are much larger sources of discrepancy from compensation curves for mic, soundcard, and shift to some (arguably debatable) target loudness curve, and the variation in mic sensitivity as a function of frequency.