once setted 1 time, after i cant plug it without driver and use all features ? or not ?
Your question doesn't make sense.
Once you set the SBX setting once, the E5 will store the setting on board and you don't need to use the driver to enable / disable it. All you need is to press the SBX button on the E5 itself. However, you still need the driver to adjust volume so you should leave the driver running on the background.