Acrylic ciems have been a negative to me. They don't seal as good as tips. Bass is definitely not guaranteed to be better unless you are willing to ship them back for the perfect fit.
Silicone ciems is where its at. Amazing isolation and will probably fit the first time. Does not need to be perfect.
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The real negative of ciems is not being able to tip roll to alter the sound to your liking.
Wider bore tips for less bass. Etc.
Because of modern iems with multi-drivers have their complexities, they do not EQ well. They aren't made to Audeze-like standards. Heck there can even be different types of drivers nowadays and not simply a complex crossover.
So Physical mods like tip rolling is way better over EQ with iems.
Quite the opposite for me. I have tried several tips and none of them fit as well as customs, provided the fitting cast was good, of course.
I also have to disagree on the EQing part: I work in audio production and I have never had issues EQing my IEMs according to needs. It wasn't until o got to Stealthsonics that I stopped doing that as I found an overall spectrum I feel at home with.
shows how different all this can be from person to person!