you have it backwards.
a speaker in the wrong box will do no harm unless you are expecting a load of bass output or if you were trying to overclock the power-handling ability of the voice coil.
Which has to do with sound. Bass is part of the spectrum. And one of the reasons most people go for speakers.
you would need about three feet of rectangled box with one 5.25inch midrange at the very end of the box for the soundwaves to become so bloody sideways pressured that the internal soundwaves affect the proper functionality of the cone.
and that means you probably have to build the box wrong on purpose.
but dont be fooled, there are some drivers that are made specifically to work in the long obnoxious rectangle boxes, and those long boxes only.
Don't have enough experience with building box speakers to make a counter point.
i really dont want to ever in my life hear you say again that the cabinet is more important than the speaker.. because that is like saying the plastic tub all of these pre-built speakers are coming with are much more the reason of the $250-$500 price tag.
and that would be embarassing for you.
The cabinet is more important than the driver. IN MY EXPERIENCE. Better? The fact I'm working on open baffle speakers and dipoles has my knowledge skewed apparently. And yes, that's sorta what I was saying. Cabinet and dampening play a big part in the sound. Maybe I overemphasized the importance, but making that basic of a cabinet (I've actually tried something like that and it sounded horrible.) isn't that viable.
anyways.. i must admit, the sound will be crappy if you expect the 5.25inch woofers to provide bass.
the 2way might provide 'base'
but that is amist total slang of the word and conjecture of the mastering of the audio.
What?
you can totally make a speaker move in and out more by putting it into a larger box.. but that means the speaker has a larger chance of slapping and bottoming out.
using speakers that use the internal volume of the box to maintain and upkeep the fidelity from a speaker is a poor design aside.
that would mean there is some really funky magnetic gap problems and demanding a specific internal volume is only duct taping a problem.
This isn't even addressing anything! Okay, if you're trying to teach me a lesson, don't try. This is completely off topic.