I don't think I could get into anime. I've tried watching it and it's always too dramatic and corny for me to enjoy. I'm not sure if The Boondocks is considered anime, but that's the only one I've watched that I've liked merely because it's funny.
You know what another show aimed towards little girls (I assume) that I enjoyed was? The Powerpuff Girls. I was watching that the other day and I still enjoy it. As a kid, I refused to watch it because 'eww it's for girls, etc.' but then my sister made me watch it and I enjoyed it since. It makes me realize that I'm getting older if Boomerang is showing cartoons from when I was a kid.