Good point, I have only been using the uDAC or Icon Mobile with a Macbook or Macbook Pro, and not something with a noisy USB port. I haven't tried them with a noisy USB source ever.
I found the Icon mobile to be a little forward sounding, and good with bass heavy recessed phones like Denon, Ultrasone, IE8 or W3, but not so good with Grados or AD2000 and lacking power with Sennheiser HD600. I also felt it sounded slightly less bright with USB as source instead of iPod, and I didn't like it as much via my iPod Nano LOD. I also posted that the uDAC (1 and 2) are better than the Icon Mobile, and still feel that way. But Icon Mobile didn't suck for $99 either - In my review I put the Icon Mobile on about the level of the iBasso D2 with some phones, better with others, and worse with some. The D2 had better detail and space, but slightly boosted lower mids/upper bass, and recessed upper mids. Neither one made it to my top tier of DAC/amps. In that respect I preferred the sound of the uDAC (original) more than either of those DAC/amps. I would prefer the iBasso D4 over any of these - it will cost you over 2x as much, however you get a bigger jump in performance and power and features that holds it own vs the big guys.