Got these to replace the RE-400s I use at work and I'm pretty disappointed, though it's really on me. Not disappointed in the sound, in fact I enjoy it quite a bit, but unfortunately the nozzles are just too wide and long to be comfortable in my small and-probably-oddly-angled ear canals. I can deal ok enough with wide nozzles but these things are pretty long too, so they just sit very uncomfortably in my ear (I can actually feel the nozzle). Using a tip that keeps the nozzle away from my ear has the unfortunate effect of making the rest of my ear uncomfortable from the housing pushing on it (in order to have both inner and outer ear comfort means a pretty crappy position that doesn't yield great sound).
Real shame, the sound signature is kinda what I was looking for but I really should have put more effort into looking at the nozzles first (knew they took T-500 comply tips; I've worn T-400 sized nozzles without issue but those have been much shorter nozzles).