exFAT is fine and is the default for cards over, I think, 32GB...something in the way to small size.
One thing I've noticed with media players in general is, if you're using a player that builds a database from tags, metadata needs to be clean. Meaning, outside of the normal artist, album, date, genre, track number and track name, the rest should be verified clean or deleted. I tag almost everything using AllMusic.com as my source and as such there's no weird random characters, but the review for an album goes into the comment tag. Those reviews can be rather wordy and that will make a scan chug along. To solve that, I kill the comment.
Maybe the A&K has a player that can handle something in the tags whereas Mango on the DX160 does not? I'm using UAPP on my 160 and it handles 40,000 tracks, though it does take hours for the initial scan.