Hi koso,
Yes, in my setup the sonic differences between SR Orange fuse and Holo Audio Nano Red fuse are very audible. The fuses Holo Audio picked for their products are excellent as well, but i am very used to the sound from SR's Orange and this could due to my own preferences. If i am not mistaken, the fuses Holo Audio uses is made by Aucharm and the specs are very similar to this one:
https://www.aliexpress.com/item/4000463109849.html I am not a technical guy and only a music lover+an "audio hardware geek", so i am not in the position to comment on fuse performance, but these are my feedbacks. To me, one particular area SR Orange fuse stands out is the ability to reveal more opened sound field and at the same time to retrieve the instrument details and effects in the music background. I feel that the difference it creates is like someone removed a set of enclosed speaker grills from your 2-channel speakers (i use speakers more than using headphone by the way). I installed SR Orange fuses in my Mcintosh solid state Preamp, Power Amp and the Linear Power Supply for my JCAT XE cards, the incremental sonic improvement are very enjoyable. I was in the beginning skeptical about fuse replacement could alter the sound of hi-fi gears, until my friend lend me his SR Blue fuse to try on my own system. I was amazed by the sonic improvement and have decided to make extensive tests on audiophile fuses for the last 3 months. I had tried many brands include some of the best rated ones like Power House Zero, SR Oranges and the made-to-order Audio Magic Ultimate Premier Beeswax fuses. I ended up keeping SR Oranges because the overall most suitable sonic characteristics with my system. Both the Audio Magic's and Power House's are nice but too warm and different dynamic as SR's for my like. So in the end i sold those fuses in Canuck's Audio Mart. I came from Asia and there is a huge market for audiophile fuses there compare to West Coast Canada. Nevetheless, both Holo Audio Red Nano fuses and SR Orange fuses are nice tweaks for my Spring 3. Just a matter of personal preferences. But i encourge you to try on your own Holo Audio DACs or preamp. The results should be favorable.
By the way, Synergistic Research has an even better performing fuse called SR "Purple" from mid-October. I bought my fuses from here:
https://highend-electronics.com/collections/accessories/fuses
There are many customer's reviews you can read from this site under each fuse listing. And the owner Alfred can give you better technical advises.
Cheers !