If you think the 325s is amusical you simply couldnt deal with the revealing highs. You are not making a rational choice here, just telling me you dislike the sound of the can and thus thinks its less good than whatever speaker gear you come up with. I am saying, again, that in terms of details and clarity, the 325s will be better than a speaker pair costing 10 times its price.
Maybe in terms of overall sound quality, including soundstage, you think speakers are better, and thats ok, because Grados arent made for soundstage, but as far as sound quality is concerned, a 2000USD speaker pair will not give you a better sound - just more realistic soundstage.
As for the 325i, I think they are a HUGE improvement over the silver 325s, so much that the 400USD difference between them and the RS-1s is imho completely ridiculous.
On another matter, I have personally heard the ML CLS IIz so I can give my thoughts on that. They are indeed great speakers, better altho different from the Dynaudio florostanders I have myself, but nowhere near the level of detailling and quality of the silver 325. I mean, we're talking about an electrostatic speaker pair here, literally crappy bass... Not even worth comparing to the 325s would it be in terms of how detailled the highs are or how good the bass is. Surely they are fast and have a good midrange, but its still not even close to the 325s paired with the right gear. The ML CLS IIz are not the right choice for a magical music experience imho... There are much better ways to spend 3500USD.