I would say you really only need iGalvanic if you have a ground loop problem. As Rob said, this is more likely when using an external amp or speaker amp.What are your opinions of a DDC for a Hugo 2, the ifi Igalvanic is an example. Do they make a difference or are they kind of unnecessary? I have a HP Omen with a i7 processor, a GTX 1060 graphics card, and a bigger fan inside for cooling purposes. Not sure if there's enough inside to create enough electrical noise to have an impact in my rig. Hugo 2 (via USB from pc to my Stellia, or the Hugo 2 to the Rotel RA-1572 integrated speaker amp via some well made RCA Cables to my speakers with the PC being my source again).
If you are hearing low level noise that seems to be related to mouse movements or changes on the screen, then a device like the iPurifier2 or iPurifier3 will stop it.
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