The Sennheiser sound tends to be warm. If you like to feel like music is a warm, fuzzy, comfortable blanket that also sounds great, then the 650 is probably the one for you.
Beyers, especially the studio oriented ones, tend to be colder and more clinical. If you like your music to be a scalpel, carefully peeling each individual layer of the song apart for you to hear, the DT48 will be better.