I finished Returnal, Remnant and Remnant 2 all co-op with a friend, he ran a DPS build and I ran a Handler/Medic. It was a blast and made a lot of the sections like boss fights (they were shredded) and the proving grounds (one at the switch, one waiting at the lift etc.) so much quicker and easier. Those games are totally about the builds. When I was grinding the Outriders DLC and matchmaking for Trials of Tarya Gratar runs, I'd jump in with people 2 apocalypse levels or more above me and the end run stat's showed I was doing 11B damage while they barely broke 2B if that at all.
We platinumed Bloodborne as well full co-op, but that took a little more work as you had to do each section twice since the host only received the progression.
All of those were on the PS5 so I had no other choice of controller.