The connectors on the headphone-side are 3.5mm mono. From the photo, the bottom part of the plug may have some chase to fix it.
Source
I collected the impedance and sensitivity of flagship headphones. Lower sensitivity (higher zone in the chart) means you need more power, and higher impedance means (right area) you need more voltage, thus making it more difficult to drive in some aspects.
And this is the power [mW] necessary to gain 100dB.
Formula: Power [mW, 100dB] = 10^((100-Sensitivity)/10).
Say, HD800s has very high impedance [300ohm], but thanks to their high sensitivity[102dB], we do not need much power [0.63mW] to drive.
On the other hand, DCA's new Expanse has a very low impedance [23ohm], but because of its very low sensitivity [86.5dB], it needs much more power [22.39mW] than Sennheiser's.
We can say YH-5000SE needs more power than Mezes but not demanding like Hifiman or Audeze.
Power is a product of Voltage and current. Voltage vs. power is like this.
Generally, if a pair of headphones demands more power, driving them is more challenging. However, in more detail, ATH-ADX5000 demands a higher ability to supply voltage to an amp than Th909 though they need a similar level of power, for example.
Moreover, I focused only on the volume (SPL, sound pressure level). But the demanded performance of an amp or "drive-ability" is determined by many aspects, not only by how easy to get loud sound.
Conclusion: YH-5000SE will not demand so much power from the amplifier, but probably slightly more demanding than Meze's flagships.