Ctn,
it is better to amplify less on a strong signal, as the signal to noise ratio is much larger, than to amplify more on a weak signal where you would tend to boost noise and hum along with the rest of the signal (poor signal to noise ratio).
cosmo,
if you look at the amplifier's specs, it may say that it needs 1.35 volts for 100 watts output (as an example), if the amplifier has a volume potentiomet, and provided the impedances are a good match, it is easier to have the source output 1.35 volts and then adjust the volume through the amplifier. if however the output impedance of the source is higher than the amplifier, then you may have problems.