No trolling.Let me proceed on the assumption that this is a serious question and not an attempt to troll. Regarding comfort, it is all subjective. ZMF is about the only manufacturer that ships you multiple sets of pads that can you can switch between - thus making a fair comparison possible. Here is comparison of various pads for the Atrium and this user rated the the Universe Suede pads (which are vegan) the most comfortable of the lot. I have read tons of ZMF headphone reviews and I have yet to read one which complained about the non-leather pads being less comfortable.
As regards how long they last, the only comment I have is that it would not matter to me even if I had to replace the pads more often. Given how much I am spending on this hobby, buying a few extra pads will not make much of a difference.
I was comparing just « regular » genuine leather vs « regular » artificial leather (« regular as opposed to suede, nubuck, daim…). And without even taking into considerarion velour, alcantara etc.
Personally I am not a fan of feeling artificial « regular » leather on my ears. It sticks, makes me sweat and gets my ears hot. I feel like having to take them off once in a while. This doesn’t happen with genuine « regular » leather - or much less.