I would say the mids are very uncoloured and accurate. While all headphones / speakers will impart a signature, I do find the MDR-7520, is quite revealing of the inherent qualities of the recording. While remaining faithful, it is also somehow not harsh, nor too soft. As such it is very good headphone for mixing and monitoring. Bass response delivers more punch and kick then sub-bass. Sub-bass is there, but a bit masked by the <40hz spectrum. For fully extended bass response, I found Sony's MDR-7550 (IEMs) to be excellent in this regard, the 7550 developed as part of the same family of studio headphones. My Denon D2000 has less punch, but a rounder, fairly flat bass response. The LCD2 goes even further, with a very linear and extended bass response.
The 7520s bass response is decidedly north of neutral. It is dialled up specifically for mixing purposes. Its important to note this, as for a listening headphone or reference, it can sound 'incorrect'. For engineers - and even DJs wishing to protect their hearing - the 7520s boosted bass helps greatly spot the lower end details in a mix. True sub-bass details should be referenced on a sub speaker, but also via scopes and instrumentation (hardware/software).
At the same time, where else is one going to find such a signature, one that isn't an Apple/Dre Beats™, but is the studio engineer equivalent. So if you like techno or electronica the 7520s are amazing, but they are also excellent for all genres. That accented bass, tightly drops off once it hits the lower mid-range, so it doesn't get in the way with acoustic recordings. You don't get the 'mid-bass' bleed that is so prevalent for many consumer cans. They do fine for classical, as they are well extended up top and their flat mid-range allows for very naturalistic instrument reproduction.
I can see how they have a bit of the Sony house sound. MDR-1r owners/admirers will notice that the driver design and baffle predate the MDR-1r, and have some signature resemblance. The MDR-1r is actually a very good headphone, but could use a bit more oomph. The 7520 is also more refined on the top end and generally more neutral. It does have the Sony 'soul' and thats good. The MDR-v6 and 7506 had this too.
I've had these phones for a while. They really could be the only closed can I need. Great combination of practicality, build and sound quality