I own the HD25 and the AKG K550. Why AKG marketed the K550 as a portable headphone, I have no clue. It really is a bit too big to be able to put anywhere and clamping force isn't enough to keep the headphones from sliding off your head if you like bopping/need to be in motion. These two headphones are like polar opposites. The Senns are somewhat neutral but have a little emphasis on the mid-bass. I've found that they sound BETTER (in my opinion anyways) in louder environments, but that may be because the outside noise is attenuating the lower frequencies. The HD25 also has a pretty narrow soundstage, and while the detail retrieval is adequate, it's not $200 worthy.
The K550, on the other hand, has an incredibly wide soundstage for a closed headphone. There's much more breathing room between instruments and detail retrieval is excellent. However, coming from the HD25 the K550 will sound very treble emphasized, and they tend to reveal poorly recorded tracks. The presentation isn't as aggressive as the HD25.
So if you like a little bit of thump and don't care about a huge soundstage, stick with the HD25, especially if you can find it cheap. If you want detail retrieval, slight treble emphasis, don't plan to move your head around much, have a place to put it, and are willing to shell out another $100, go for the AKG K550. The AKG's are the better headphone by far in my opinion, but they may not suit your needs.