These are FANTASTIC headphones.
The sound quality is superb, and they far outclass my other sony mdr-ex71slw 'phones. I have have the excellent Sennheiser PX100's which I'll try to compare to.
Sound:
Bass...excellent and deep. Unlike the Sony's however, they don't output overblown baggy bass, it is very tight and tuneful and FAST (Bass starts and stops on a dime with the CX300's). To give an example, various dance tracks that have complex bass-lines tended to come over as a slightly homogenous deep sound only on the Sony's, whereas here they are easily distinguishable from each other...all separated, present and correct.
The Sennheiser PX100's don't reach as deep, but they do tend to vibrate instead...thus giving the impression of deep deep bass (whereas with the CX300's, it's real !)
Midrange...lovely liquid midrange here. Stands out nice and clear, vocals sound like they're physically in your head. Unlike the Sony's, NOT drowned out amongst shrill treble and innaccurate bass.
The midrange is as clear and well proportioned as the PX100's.
Treble...Yes, OK, they do have slightly high treble on first listen, but you need to burn them in first (3 days continuous listening so far). I've also use a bit of cotton wool in the opening until then to tame the top end somewhat (works very well, and good temporary fix until burn in complete). Treble is nicely placed, giving the impression of a nice wide soundstage (to the extent that sounds appear to come from not only inside your head, but also around you sometimes).
The treble in the PX100's is also very clear, giving the impression of nice open soundstage (slightly more expansive too) but the Sony's, conversely, are terrible screechy rubbish.
Build Quality: Exemplary. Better than the PX100's (which are excellent anyway) my silver CX300's aren't simply covered in cheapo silver paint/plastic. It actually looks like metallic car paint with a few coats of piano gloss veneer over it (I was a bit worried that I hadn't opted for the "safe" black ones, but the silvers look great imho).
The material is also very solidly put together. In this respect, you get the impression manipulating them in your fingers of a classy piece of kit.
The Sony's, on the other hand, have appalling build quality using cheap nasty materials.
Comfort: Again top notch. So comfortable that you forget you're waring them. They're supplied with 3 sizes of rubber "canal-piece" so you have choice like the Sony's. For comfort I'd rate these as high as the Sony's and this also means very little sound leakage.
The PX100's, while good, aren't quite this good and you also get more sound leakage with them
Overall c.f. the PX100's the sound of the CX300's is very similar with only the soundstage being not as wide and open, but traded off for a much nicer fit with less sound leakage.
The Sony's come in a distinct 3rd in all departments apart from comfort.
PS I would also agree that I use the PX100's when I also need ambient sound intrusion (like on a bike), and the CX300's when I don't want to disturb others (on the train).