Mul-T-Lock, Medeco, ASSA Twin and Abloy are all UL437 listed high security cylinders from ASSA-Abloy. Primus is a UL437 high security cylinder from Schlage, part of Ingersoll-Rand.
I wouldn't attempt to pick any of them, except as an exercise. The UL437 rating indicates that they have passed very stringent tests to certify that they will resist picking, drilling, pulling and other forms of attack for specific intervals.
Mul-T-Lock keys can be easily decoded with a dedicated key machine. A locksmith used to pinning these cylinders and cutting the keys can decode a key by sight, both for the outer and inner pins.
Medeco Original is easy to decode by sight. Medeco BiAxial is a little tougher to decode because the pins are not just set to different rotations and depths, they are also set to Fore and Aft in each pin cell. There is, however, a handy flat decoder that every locksmith that works with Medeco has in their kit.
ASSA, Abloy and Primus are all easily decoded by sight. Also with a cheap gauge for the respective keys.
What gives all of these cylinders their high level of security, apart from the UL437 specs is key control. Distribution and creation of the key blanks is tightly controlled and protected by the individual manufacturers through patents and user contracts. Run afoul of the manufacturer and you end up with no stock being shipped, your existing stock seized and your sorry ass hauled into civil court.
Medeco keys are hard on pockets and used to be notorious for breakage many years ago. They are substantially better now. I find Abloy to be user unfriendly because you have to turn them to align the discs with the sidebar, then turn again to actually work the lock. They are damned tough cylinders, though. The caes-hardened steel nose just spins when you put a drill bit to it.
A good lube for any of these cylinders is Tri Flow or something similar, depending on your specific climate conditions. Don't use graphite as it can be abrasive in long-term use with a tight tolerance cylinder.
My 2 cents. Hope some of this information is helpful.