My impressions of the ms-1 (using modded ratshack pads)
It definitely has a very warm sound, which I enjoy a lot, as well as still being a bright phone. The bass is tight, but doesn't go as deep as the sr-225, but some of the bass detail is lost on more complex passages. (example being a barely audible bass guitar) I feel the shure e2c bests it at detail, though not by very much. That might be attributed to the isolation. I really love the mid-rage, it makes electric guitars just sound so much fun. The highs are, what I feel, the worst sound aspect of the headphone. It's rolled off and slightly grainy compared to the sr-225. Soundstage is minimal, but collapses even further with the use of the modded ratshack pads.
Overall, its a warm, fun sounding can with a high-end that could be cleaned up a little bit. I think its a great starter can for an aspiring Team Grado member. I do like the grado sr-225 which I listened to, but the ms-1 is still a good headphone for $100.
edit - I use them unamped out of my chaintech av-710, but am acquiring an amp VERY soon. I'll tell you how it goes once I get the amp.