well, these are two completely different products..do you mean the PCI 0404 or the 0404USB? those two cards only play ASIO bit-matched, so for DS/WASAPI you're forced to select the right sample rate manually in the drivers, otherwise they will be resampled.
The 0404USB runs AK4396 and non-swappable 5532 opamps, and has tons of features you -most likely- don't need. but it seems to be using async USB drivers and isn't limited to 16/48 over USB like the Spitfire MKII.
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