I realize this is an old thread but I thought I'd put in my 2 bits.
I've been using the HD800 with X3 exclusively for the last 2 months cos' I can't quite bear to cough up the cash to buy something better. I'm running the X3 as a DAC/AMP from my PC which plays FLACs, mostly standard CD quality. I listen to mostly classical, soft rock and modern worship.
I usually put my PC at about 75% output, place the X3 on high gain and the volume is typically 25-35, with 30 being about the average figure so I think the X3 has sufficient power to drive this headphone.
I think the combination is just wonderful and I really enjoy the music, even better than with my JH Roxannes (considering the X3 was primarily designed to support portable music). I can hear more details, or at least hear them more easily with the HD800 compared with the Roxannes. Bass is also outstanding, full and detailed. I can hear the shimmering of the cymbals clearly which I really enjoy.
I guess a more expensive setup may sound better but for now I'm just enjoying the music and I think that's the most important bit
BTW: I've also listened to the Telarc recording of Tchaikovsky's 1812 with the "digital canons" as brought up in the previous post. They are simply amazing with the HD800s and the details of that almost cacophonous bells section at the last bit is simply superlative.