unless your computer is a Mac, or a desktop PC with a $100+ dedicated sound card..the DAC and what not is probably better on your ipod >_< i recommend LOD with ipod. that gives you a pure DAC straight from analog signal from ipod
will you notice a difference from desktop(let's assume a regular laptop) and ipod with E11 through 3.5? ....? i dont' know about you. but for my computer.. it's night and dusk. which means it is kinda close but u can still tell a diff. oh and btw. if you use with comptuer or ipod through 3.5mm jack(get an lod) set volume to about 60% so you aren't maxing out your devices amp which adds hiss, distortion etc to it. any other questions.
did you read? how was it?? oh plz note. i didn't say anything about E11,E10,or E7 being able to do anything at all. just conjecture or recommend it. i just did general sound properties in my posts and things on E17 (hint hint for anybody else reading)