I also have the GTXP, and although it's pretty nice in the realm of PC sound, it's still PC sound. MP3s sound really nice through my monsoon comp speakers, but I hooked the laptop up to my Integra amp one day to listen to some of the rips, and WOW, it sucks the big one. I increased the bitrate quite a bit as an experiment, but there is still quite a difference. It is, after all, a lossy compression scheme, and it's not too hard to hear it.
I have seen threads where people want to hook up their Klipsch PC speakers in the livingroom to make a "bitchin' stereo system". They may sound nice on the computer, but in the livingroom, there are a LOT of other speakers that will sound much, much better.
Plug a standalone Cd player or DVD player into the META and give it a listen, as compared to hearing it play through your headphone jack. I'd be surprised if the difference is not quite pronounced, unless you happen to own mostly Mark Levinson stuff or some other high-end hardware.
Another thing that was a real learning experience for me was to construct a healthy but simple cmoy for the purposes of listening to different op-amps, as Tangent describes in his website. Mine has 1uF film and foil polypro coupling caps (so I can use it with any source, regrdless), and the PS has the divider resistors replaced with a railsplitter and a pair of BUF634s. There is the extra cap upstream of the BUFs per BDX's supply, and the last pair on the PSU box are non-polar. The boards for both the PSU and the amp are mounted on top of the enclosures, with the wiring inside running to the pot and jacks. No buffering or second op-amp output stages- all you hear is the op-amp. Being able to listen/kill power/swap chips/repower/listen makes even the suble difference between chips noticible, firsthand. And no, I don't even own HD600s. I have a pair of 497s, a pair of 570s, and a pair of SR80s.
An amp can help with a PC setup (especially fi you use high-impedance cans, but you have to ask why), but the benefits are not as likely to be so pronounced, IMHO. Frequently, the added resoulution only serves to magnify the shortcomings of the source.