Like 12bh7's, it isn't an exact analog of a 12au7. As PJ explains it on bottlehead: "In the Crack circuit the E80CC will bias up at a higher voltage (mu is 27, vs. 17 for the 12AU7), changing the 6080 operating point as well. This will increase the cathode resistor or Speedball heat dissipation - I don't know by how much. It is NOT a direct replacement, even though it may work in many circuits designed for the 12AU7." The higher mu is also going to translate into higher gain which may or may not be an issue for you depending on your source, attenuator an
whether or not you're comfortable padding your pot. (see
http://www.goldpt.com/mods.html)
Also FWIW, I agree with olegausany that the GEC 6as7g's are very nice, quiet tubes (with a cool internal structure), but the prices they go for these days are totally outrageous. Skylab was a big proponent of this tube for a long time, but if you read the 6as7 thread, even he discourages buying them now due to the silly pricing. I own one and after considerable A/B'ing, do not think it is any better from a sonic standpoint than the best of my cheap mil spec 6080's. Moreover, for about 1/3 the cost of a GEC, you can get a nice 5998, 7236 or (if you're really lucky) 7802 - all of which actually lower the output impedance of crack, providing tighter bass. The only people I've seen pushing GEC's as a "must have" tube, also happen to have purchased them in volume, at a discount, and will be happy to sell you a pair for the modest price of $400.