Balanced is prefered in pro-audio because it is
safe. You don't risk
down time in a studio and you definitely don't want to disrupt a live show! Different priorities!
Not only the connection but the gear too. Many people believe that what's good for a studio is good for home. Wrong!
Speakers for nearfield monitoring are
not exactly musical and rack gear is not the last word in musicality either. The advantage of a home hobbyist is that he
can afford down time and/or
endless tweaking in order to experiment for the best sound. Take advantage of that
luxury!
Now to your specific question. My answer is: it depends on the gear. Here is a real case. My friend had a dCS Verdi DAC and a Spectral amp, both offer XLR and RCA jacks and both can invert phase at will. Why do I mention that? Well, if you invert phase in both, the end result is
no inversion, so theoretically it's the same as both units not inverting phase. Not true in real life. Turned out that when both invert phase, the XLR connection sounded better, otherwise the RCA sounded better.
This has nothing to do with the phase inversions, just with the
internal circuitry in that specific path. For some reason, it worked its way in that manner. I'm sure there was no intent by the engineers to do so...
The only way to find such an anomaly is by trial and error and that goes back to the fundamental question: do you want a
safe receipe for the home environment or would you rather invest more of your energy to
extract the best your gear can
potentialy give?
To me, the latter is a great advantage and it results in a lot more rewarding sound. Now we are talking subjectively... To me,
simplicity is the way to achieve the best (a very subjective word!) sound. I favor purity of tone over abundance of detail and analytic dissection of sonic cues. I favor integration of tones as one performance over the last word in deep bass response or a super-flat (as though it's achievable...) frequency response. I'll take some cabinet resonance as a trade-off for smooth transition between drivers. I also much prefer simple amplifier circuits over very complex ones. Unlike what common thinking seems to be, there is no free lunch!
You add circuitry - you will
pay for it one way or another. You might get diminishing levels of distortion but you will lose another aspect of audio purity and it all boils down again to personal preferences. The studio guy doesn't have that much freedom, in most cases!
Everything I listed above is very subjective, reflecting my own preferences. Regardless, even if your set of preferences differs from mine, I still believe that the true way for
your audio perfection is not the
safe solution. Don't succumb to misconceptions
!!! Experiment with balanced, single-ended and other aspects of your system - and you shall be greatly rewarded!!!