Clutz
Tells us when we're offset.
- Joined
- Jun 7, 2002
- Posts
- 2,483
- Likes
- 13
Quote:
Your friend is totally wrong. Actually, we develop antibiotics at a relatively slow rate. I used to know more about this a few years ago, but in general it takes about 10 years for the development of a new antibiotic, and the amount of time until the occurrence of bacteria resistant to the new antibiotics are decreasing. Furthermore, evolution proceeds at a rate proportional to population size, mutation rate, and inversely proportional to generation time. Bacteria generally have extremely large population sizes, very high mutation rates (compared to higher organisms), and very short generation times = very adaptable organisms. Add to that the whole concept of a 'species' is a little bit vague when it comes to bacteria (there is ~50% genetic variation among various strains of E. coli - that's more genetic variation than separates all the primates from each other by a long shot, just to put it in perspective). Bacteria are able to 'exchange' genes for antibiotic resistance with each other, so bacteria don't have the problem that most organisms have where each species / strain of bacteria has to independently evolve resistance - they only have to come into contact with a compatible strain/species that has evolved resistance, and either exchange plasmids, or in some cases one bacteria consuming the other.
Antibiotic resistance is an area I actively research (I'm a professional biologist), and it is a much bigger problems than is generally accepted/known.
On the topic of how long to take antibiotics for? Complete your course of antibiotics. Is 5 days enough? 7 days? 10 days? Who knows - it depends on the details of the infection you have - if it already has some resistance, what the total population size is, etc. I would take it for as long as it is prescribed. Is it really that inconvenient to take your pills three times a day for an extra few days?
Originally Posted by ZepFloyd /img/forum/go_quote.gif I know people and have said that with all the antibiotics that are prescribed germs/bacteria are learning to resist it. A friend of mine brought up a good point though...we develop medicine so quickly now that it doesnt seem likely germs/bacteria will ever be able to evolve and resist treatments. |
Your friend is totally wrong. Actually, we develop antibiotics at a relatively slow rate. I used to know more about this a few years ago, but in general it takes about 10 years for the development of a new antibiotic, and the amount of time until the occurrence of bacteria resistant to the new antibiotics are decreasing. Furthermore, evolution proceeds at a rate proportional to population size, mutation rate, and inversely proportional to generation time. Bacteria generally have extremely large population sizes, very high mutation rates (compared to higher organisms), and very short generation times = very adaptable organisms. Add to that the whole concept of a 'species' is a little bit vague when it comes to bacteria (there is ~50% genetic variation among various strains of E. coli - that's more genetic variation than separates all the primates from each other by a long shot, just to put it in perspective). Bacteria are able to 'exchange' genes for antibiotic resistance with each other, so bacteria don't have the problem that most organisms have where each species / strain of bacteria has to independently evolve resistance - they only have to come into contact with a compatible strain/species that has evolved resistance, and either exchange plasmids, or in some cases one bacteria consuming the other.
Antibiotic resistance is an area I actively research (I'm a professional biologist), and it is a much bigger problems than is generally accepted/known.
On the topic of how long to take antibiotics for? Complete your course of antibiotics. Is 5 days enough? 7 days? 10 days? Who knows - it depends on the details of the infection you have - if it already has some resistance, what the total population size is, etc. I would take it for as long as it is prescribed. Is it really that inconvenient to take your pills three times a day for an extra few days?