obobskivich
Headphoneus Supremus
So that's three. I think Bioshock (the first one at least) uses EAX 4, but I could be wrong (I get the "Enable EAX" option with both the Audigy 2 ZS and X-Fi, so I assume it's EAX 4; it may well have some backwards compatibility support though - 4 seems a lot more common than 5 having said that).
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(Like I said before) F.E.A.R. also uses EAX 5.