I have a portable amp which i let it charge from the desktop usb port all the time. However when i use it, i am lazy to disconnect it's charging cable and end up it's hissing a lot. Is there any product that can clean the power from usb port to allow cleaner energy which will make my amp reduce the hissing sound.
There probably are various products on the market that claim to do this, however you're most likely to pay way to much for something that may not work at all (because of point 3).
There are three options I can give you:
1. There
this device from Aqvox, which separates usb power delivery and data transmission at the plug. Don't know how much this costs I'm afraid.
2. Charge with a higher quality external 5V charger. The folks over at Grace Design tested and measured a whole lot of external usb chargers and are selling what they found to be the best/quietest one for a very reasonable price
here (bottom of page), to go with their m9xx. I don't know whether this could work for you, because you don't mention what amp your have. It could be that usb power and data go over the same cable, in which case an external charger cannot be used.
3. Alternatively, the hissing could be to a ground loop. I know this because I have acquired the above mentioned Grace m9xx a short while ago, and had noise problems via the usb connection, that sounded totally different from any grounding problem I had ever encountered. Still, proper grounding solved the issue completely, which surprised me. What proper grounding is all about, is making sure that every device in the audio chain is
grounded at one point only. Remember that usb cables and RCA cables or other audio cables connecting various devices also connect their grounds together. So if your computer is grounded, make sure that none of the audio devices is grounded via its power plug, because that way your amp will be connected to ground at two points: via its audio cables via another device such as pc,
and via its own power plug. In such a case, you can't disconnect the ground on the audio cables, meaning that you must lift the ground at the power plug.
If you give more information about your setup, we may be able to help you better.