BoyT ---
I find best results with the tri-flange. The trick is to insert the flange very very deep until the outside world sounds submerged. Try different angles for each ear canal, as my canals each have somewhat different paths.
The foamies provide a reliable average quality seal, but they wear out quickly and are costly to replace. The flanges need more adjustment and experimentation, but once you get down to a routine they will give you better isolation and bass, and can be played at a lower volume and still drown out the outside world.
Keep the flanges clean. Order a new pack and rotate two sets until one wears out. I wear one set for a week, clean the wax off after every removal, and wash the set with warm water and soap at the end of the week. They then sit and dry out for the next week while I use the other pair in rotation.
I don't recommend moist insertions. Using your own spit (the most common solution) is gross and a bad sanitary idea IMO. And carrying around chapstick or KY jelly or whatever the heck other ointments people recommend is even weirder and takes a lot of the fun out of using the phones. "Hmm, let me put some more jelly on the phones before I insert them!" Freakish and prophylactic. I get a perfect seal without this procedure, and don't alarm my fellow commuters as I coat my ERs with lip balm and then shove them into my ears...
If one phone ever stops working, odds are good that the filter has gotten wet with water or sweat. Let the phones dry for a half day or so and they'll be fine. There is probably no need to change the filter. Once you learn not to panic and change the filter when this happens, you can go six months or even a year without changing filters. (Assuming you keep the tips clean as reccd above.)
Always be aware of your surroundings. Even a stroll in your neighborhood can be risky with Etys as you may not hear the fire truck screaming towards the intersection where you have right of way or the screams of alarm as the psychopathic ax murderer closes in on you from behind... (your neighborhood may vary of course, but awareness and discretion in use of your Etys is always a good idea.)
Register the ER6is online with Ety to get the full one year warranty rather than the 90 day one that comes with purchase alone.
Good luck and enjoy your listening!