The HD650 is harder to power in my experience, but the impedance is the same and the figures don't really show it that way. However, the HD650 will be lacking in transparency, dynamic range, and bass control, which you really don't measure for usually, until it's finally properly powered, which will most likely involve a balanced amp of some sort. The HD600 may be a bit less sensitive and may need more gain, but it will become transparent and controlled on less powerful systems than the HD650. You can probably get away with a simple single-ended amp as long as it's a good one.
Both headphones are also massively revealing when they're given enough power to properly open up, so you will want a good source. They're capable of performance that's much more high-end than the pricetag would suggest. If they were $1500 people would probably respect them properly and only use them in quality systems, but because of the pricetag a lot of people will match the HD650 with a portable amp and an ipod, and then wonder what the fuss is all about.