In my experience - virtually all the Grado pads (apart from the Jumbos) will end up giving you some discomfort after extended listening. You do get used to it - if you love the Grado house signature, you learn to
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Just in case you haven't seen it - this might help a little:
http://www.head-fi.org/a/grado-pad-choices-and-mods
Oh - and you're likely to get a lot of different responses - as comfort and sound tends to be a very personal thing. I've tried all of the pads with my MS1is (very similar to your SR80i) - and my thoughts:
S-cush (comfies) that came with the grados - I personally found them scratchy and uncomfortable.
Senn 414 - softer than the comfies, better after washing with a mild fabric softener.
TTVJ flats - I still found them uncomfortable after extended listening - but they do indeed add bass without changing the mid-range too much.
L-cush (bowls) - my pads of choice. Still can only listen to them for 2-3 hours, then ears get sore - but best sounding and, for me, more comfortable than most fo the other options.
G-cush (jumbos) - the most comfortable because they are completely over ear. They increase sound-stage, but reduce bass, and give a boost (or at least change) the upper treble. Bass became quite thin and the highs became very hot and tizzy. Not a great sonic experience.
I would suggest you do what I did though, and at some stage, buy most of them because the only way you'll know is to compare. I ended up reselling the ones I didn't like. Usually you'll find someone else around who's doing the same thing you are and wanting to try new pads - so the loss shouldn't be too much.
Hope this helps a little.